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姓名 林慧茹 Hui-Ju Lin   

網路初診掛號

網路複診掛號

性別
科室 兒童眼科
職稱 科(室)主任
經歷
1.中國醫藥大學 附設醫院 眼科部 主治醫師 (82/8)
2.中國醫藥大學 附設醫院 眼科部 科室主任 (86/8)
3.中國醫藥大學 中醫學系 助理教授 (94/12)
4.中國醫藥大學 中醫學系 副教授 (98/4)
學歷、資格證明
1.中國醫藥大學 中醫學系 學士 (71/7---78/7)
2.中國醫藥大學 醫學研究所 碩士 (89/7 – 91/7)
3.東海大學 生科系 生醫組 博士 (92/7 -- 96/7)
特殊專長
1.小兒斜弱視矯正
2.小兒近視治療
3.早產兒視網膜病變
4.白內障手術
得獎
Published papers

1. Lin HJ, Wan L, Tsai Yh, Chen WC, Tsai SW, Tsai FJ. The association between lumican gene

polymorphisms and high myopia. Eye 2009 Jul. [Epub ahead of print]

2. Lin HJ, Wan L, Tsai Y, Chen WC, Tsai SW, Tsai FJ. Muscarinic acetylcholine receptor 1 gene polymorphisms associated with high myopia. Mol Vis. 2009 Sep 4;15:1774-80.

3. Lin HJ, Wan L, Tsai Y, Liu SC, Chen WC, Tsai SW, Tsai FJ. Sclera-related gene polymorphisms in high myopia. Mol Vis. 2009 Aug 20;15:1655-63.

4. Lin HJ, Kung YJ, Lin YJ, Sheu JJ, Chen BH, Lan YC, Lai CH, Shu YA, Wan L, Tsai FJ. Association of the Lumican gene functional 3' UTR polymorphism with high myopia. Invest Ophthalmol Vis Sci. 2009 Jul 30.

5. Li YC, Lin HJ, Yang JH, Yang JS, Ho HC, Chang SJ, Hsai TC, Lu HF, Huang AC, Chung JG. Baicalein-Induced Apoptosis via Endoplasmic Reticulum Stress Through Elevations of Reactive Oxygen Species and Mitochondria Dependent Pathway in Mouse-Rat Hybrid Retina Ganglion Cells (N18) Neurochemical Research 2009 Mar;34(3):418-429.

6. Liu HP, Lin YJ, Lin WY, Wan L, Sheu JJ, Lin HJ, Tsai Y, Tsai CH, Tsai FJ. A novel genetic variant of BMP2K contributes to high myopia. J Clin Lab Anal. 2009;23:362-367.

7. Lu HF, Lai KC, Hsu SC, Lin HJ, Yang MD, Chen YL, Fan MJ, Yang JS, Cheng PY, Kuo CL, Chung JG. Curcumin induces apoptosis through FAS and FADD, in caspase-3-dependent and -independent pathways in the N18 mouse-rat hybrid retina ganglion cells. Oncol Rep. 2009;22:97-104.

8. Chen TC, Lai KC, Yang JS, Liao CL, Hsia TC, Chen GW, Lin JJ, Lin HJ, Chiu TH, Tang YJ, Chung JG. Involvement of reactive oxygen species and caspase-dependent pathway in berberine-induced cell cycle arrest and apoptosis in C6 rat glioma cells. Int J Oncol. 2009;3:1681-90.

9. Lu HF, Lai KC, Hsu SC, Lin HJ, Kuo CL, Liao CL, Yang JS, Chung JG. Involvement of matrix metalloproteinases on the inhibition of cells invasion and migration by emodin in human neuroblastoma SH-SY5Y cells. Neurochem Res. 2009;34:1575-83.

10. Kuo TC, Yang JS, Lin MW, Hsu SC, Lin JJ, Lin HJ, Hsia TC, Liao CL, Yang MD, Fan MJ, Wood WG, Chung JG. Emodin has cytotoxic and protective effects in rat C6 glioma cells: roles of Mdr1a and nuclear factor kappaB in cell survival. J Pharmacol Exp Ther. 2009;330:736-44.

11. Tsai YY, Chiang CC, Lin HJ, Lin JM, Wan L, Tsai FJ. A PAX6 gene polymorphism is associated with genetic predisposition to extreme myopia. Eye 2008 Apr;22(4):576-581.

12. Lin JM, Tsai YY, Wan L, Lin HJ, Tsai CH, Tsai FJ*, Tseng SH. Complement factor H variant increases the risk for early age-related macular degeneration. Retina-The journal of retina and vitreous disease 2008 Nov;28(10):1416-1420.

13. Lin JM, Wan L, Tsai YY, Lin HJ, Tsai Y, Lee CC, Tsai CH, Tseng SH, Tsai FJ. Vascular endothelial growth factor gene polymorphisms in age-related macular degeneration.American Journal of Ophthalmology 2008 Jun;145(6):1045-1051.

14. Lin JM, Wan L, Tsai YY, Lin HJ, Tsai Y, Lee CC, Tsai CH, Tseng SH, Tsai FJ. Pigment epithelium-derived factor gene Met72Thr polymorphism is associated with increased risk of wet age-related macular degeneration. American Journal of Ophthalmology 2008 Apr;145(4):716-721.

15. Lu HF, Chen YS, Yang JS, Chen JC, Lu KW, Chiu TH, Liu KC, Yeh CC, Chen GW, Lin HJ, Chung JG. Gypenosides induced G0/G1 arrest via inhibition of cyclin E and induction of apoptosis via activation of caspases-3 and -9 in human lung cancer A-549 cells. In Vivo 2008 Mar;22(2):215-221.

16. Tsai YY, Lin JM, Wan L, Lin HJ, Tsai Y, Lee CC, Tsai CH, Tsai FJ, Tseng SH. Interleukin gene polymorphisms in age-related macular degeneration. Investigative Ophthalmology Visual Science 2008 Feb;49(2):693-698.

17. Lin JM, Wan L, Tsai YY, Lin HJ, Tsai Y, Lee CC, Tsai CH, Tsai FJ, Tseng SH. HTRA1 polymorphism in dry and wet age-related macular degeneration. Retina 2008 Feb;28(2):309-313.

18. Lin HJ, Chao PD, Huang SY, Wan L, Wu CJ, Tsai FJ. Aloe-emodin suppressed NMDA-induced apoptosis of retinal ganglion cells through regulation of ERK phosphorylation. Phytotherapy Research 2007 Nov;21(11):1007-1014.

19. Lin HJ, Lai CC, Lee Chao PD, Fan SS, Tsai Y, Huang SY, Wan L, Tsai FJ Aloe-Emodin Metabolites Protected N-Methyl-D-Aspartate-Treated Retinal Ganglion Cells by Cu-Zn Superoxide Dismutase. Journal of Ocular Pharmacology and Therapeutics 2007 Apr;23(2):152-171.

20. Yu FS, Yang JS, Lin HJ, Yo T, Tan TW, Lin YT, Lin CC, Lu HF, Chung JG. Berberine Inhibits WEHI-3 Berberine Inhibits WEHI-3 Leukemia Cells In Vivo. In Vivo 2007 Mar;21(2):407-412.

21. Lin YT, Yang JS, Lin HJ, Tan TW, Tang NY, Chaing JH, Chang YH, Lu HF, Chung JG.Baicalein induces apoptosis in SCC-4 human tongue cancer cells via a Ca2+-dependent mitochondrial pathway. In Vivo 2007 Nov; 21(6):1053-1058.

22. Lin JP, Yang JS, Chang NW, Chiu TH, Su CC, Lu KW, Ho YT, Yeh CC, Mei-Dueyang, Lin HJ、Chung JG. GADD153 Mediates Berberine-induced Apoptosis in Human Cervical Cancer Ca Ski Cells. Anticancer Research 2007 Sep;27(5A):3379-3386.

23. Huang AC, Lin TP, Weng YS, Ho YT, Lin HJ, Huang LJ, Kuo SC, Chung JG. Ethyl 2- [N-m-chlorobenzyl- (2'-methyl)] anilino-4-oxo-4,5-dihydrofuran-3-carboxylate (JOT01006) induces apoptosis in human cervical cancer HeLa cells. Anticancer Research 2007 Jul; 27(4B):2505-2514.

24. Hsu SC, Kuo CL, Lin JP, Lee JH, Lin CC, Su CC, Lin HJ, Chung JG. Crude Extracts of Euchresta formosana Radix Induce Cytotoxicity and Apoptosis in Human Hepatocellular Carcinoma Cell Line (Hep3B). Anticancer Research 2007 Jul;27(4B):2415-2426.

25. Lin HJ, Tsai FJ, Hung P, Chen WC, Chen HY, Fan SS, Tsai SW. Association of E-Cadherin Gene 3'-UTR C/T Polymorphism with Primary Open Angle Glaucoma. Ophthalmic Research 2006 Jan;38(1):44-48.

26. Lin HJ, Yang JS, Yang JH, Fan SS, Chang WC, Li YC, Chung JG. The Role of Ca2+ on the Diallyl disulfide-induced apoptosis in retina ganglion cells (N18). Neurochemical Research 2006 Mar;31(3):383-393.

27. Lin HJ, Wan L, Tsai Y, Tsai YY, Fan SS, Tsai CH, Tsai FJ. The TGFbeta1 gene codon 10 polymorphism contributes to the genetic predisposition to high myopia.
Molecular Vision 2006 Jun;12:698-703.

28. Wu CC, Lin JP, Yang JS, Chou ST, Chen SC, Lin YT, Lin HJ, Chung JG. Capsaicin induced cell cycle arrest and apoptosis in human esophagus epidermoid carcinoma CE 81T/VGH cells through the elevation of intracellular reactive oxygen species and Ca2+ productions and caspase-3 activation. Mutation Research 2006 Oct;601(1-2):71-82.

29. Chang YH, Lin HJ,* Li WC. Clinical evaluation of the traditional Chinese prescription

“Chi-Ju-Di-Huang-Wan” for dry eye. Phytotherpy Research 2005;19:349-54 (SCI) (* Corresponding author)

30. Lin HJ, Tsai CH, Tsai FJ, Chen WC, Tsai SW, Fan SS. Distribution of oxidation enzyme eNOS and myeloperoxidase in primary open angle glaucoma. Journal of Clinical Laboratory Analysis 2005;19:87-92. (SCI)

31. Lin HJ, Tsai CH, Tsai FJ, Chen WC, Chen HY, Fan SS. Transporter associated with antigen processing gene 1 codon 333 and codon 637 polymorphisms are associated with primaryopen angle glaucoma. Molecular Diagnosis 2004;8:245-252. (SCI)

32. Tsai FJ, Lin HJ,* Chen WC, Tsai CH, Tsai SW. A codon 31 ser-arg polymorphism of the WAF-1/CIP-1/p21/tumor suppressor gene in Chinese primary open angle glaucoma. Acta Ophthalmology Scandinvida 2004;81:76-80. (SCI) (* Corresponding author)

33. Tsai FJ, Lin HJ,* Chen WC, Chen HY, Fan SS. Insulin-like growth factor-II gene polymorphism is associated with primary open angle glaucoma. Journal of Clinical Laboratory Analysis 2003;17:259-63. (SCI) (* Corresponding author)

34. Lin HJ, Tsai SC, Tsai FJ, Chen WC, Tsai JJ, Hsu CD. Association of interleukin 1 beta and receptor antagonist gene polymorphism with primary open angle glaucoma. Ophthalomiga 2003;217:358-64. (SCI)

35. Lin HJ, Tsai FJ, Chen WC, Shi YR, Hsu Y, Tsai SW. Association of tumor necrosis factor alpha-308 gene polymorphism with primary open angle glaucoma in Chinese. Eye 2003;17:31-34. (SCI)

36. 施君達、林慧茹 Traumatic corneal abscess after radical keratectomy. Transaction of Ophthalmological Society 2003;41:538 ~ 542.

37. 林慧茹、林正介、蔡詩偉、林鴻志、蘇百弘 Risk Factors of Retinopathy of prematurity in low birth body weight infants. Chinese Medical Journal (Taipei) 2003;66:662-8. (MI)

38. 林慧茹、江宜平、林建廷 Primary Conjunctiva Lymphoma. Acta Societatis Ophthalmologicae Sinicae 2002;43:77 ~ 79.

39.林慧茹、陳汶吉、蔡輔仁、蔡詩偉 Distribution of p53 codon 72 gene polymorphism with primary open angle glaucoma. British Journal of Ophthalmology 2002;86:771-3. (SCI)

40. 林瑋德、施怡如、蔡輔仁、李正純、林慧茹 Identification of a polymorphism (D168N) in the XRP2 gene in Chinease. Hum Mutat 2001;17:354. (SCI)

41. 蔡輔仁、Yang CF、鄔哲源、林慧茹、Lee CL、蔡長海 A novel mutation k167X of XLRS1 gene (RS1) in a Taiwanese family with X-linked juvenile retinoschisis. Hum Mutat 2000;16:449. (SCI)

42. 陳宏任、李揚銘、翁林仲、周介仁、林慧茹 Scanning laser polarimetry in evaluation of nerve fiber layer thickness for normal Taiwanese. Kaohsing J Med Sci 2000;16:223 ~ 32 (MI)
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